at the Amazon River, a poacher hides from an unknown creature in his boat. while it breaks through the boat and tries to catch the poacher, he commits suicide by using shooting himself to prevent it from killing him.
in the meantime, a film team is taking pictures a documentary approximately the Shirishamas, a protracted-misplaced indigenous Amazonian tribe. The team consists of director Terri Flores, cameraman and adolescence friend Danny rich, production supervisor Denise Kalberg, Denise's boyfriend and sound engineer Gary Dixon, narrator Warren Westridge, anthropologist Professor Steven Cale, and boat skipper Mateo. The organization encounters stranded Paraguayan snake hunter Paul Serone, who convinces them he can help them locate the Shirishamas. most of the group are uncomfortable around Serone, and Cale clashes with him several instances approximately Shirishama lore. subsequently, Cale is stung through a wasp, and an hypersensitivity swells up his throat and leaves him subconscious. Serone performs an emergency cricothyrotomy, seemingly saving Cale's life, but quickly after, he is taking over the boat, forcing the group to assist him gain his true aim: searching down a massive document-breaking green anaconda he had been monitoring, which he believes that he can seize alive.
Danny, Mateo and Serone seek the wreckage of the poacher's boat. A photo in an old newspaper exhibits that Mateo, Serone, and the poacher had been operating together to seek animals, consisting of snakes. Leaving the poacher's deliver, Mateo falls into the water, in which the large woman anaconda, measuring 25 ft (7.6 m), attacks and kills him, even as Danny and Serone return to their boat, ignorant of Mateo's destiny. Serone guarantees that if the team helps him locate the snake, he'll help them get out alive. That night time, the anaconda attacks the boat group. Serone attempts to capture the snake, but it coils around Gary, crushing him. Terri tries to shoot the anaconda to save him, however Serone knocks her gun away and the snake devours Gary, leaving Denise heartbroken in tears. The group overpowers Serone and ties him up as punishment.
tomorrow, the boat will become caught at a waterfall, requiring Terri, Danny, and Westridge to enter the water to winch it loose. Denise confronts Serone and tries to kill him to avenge Gary's dying, but he strangles her along with his legs earlier than dumping her corpse into the river. The anaconda returns, and Westridge distracts it lengthy sufficient for Terri and Danny to go back to the boat while Westridge ascends the waterfall. Serone breaks free at some stage in the assault and assaults Danny. The anaconda climbs a tree and attacks Westridge, but the tree snaps. The crew finally ends up in the water, Cale wakes up inside the process, and Westridge is killed inside the fall from the waterfall. The snake assaults Danny, however Terri shoots it inside the head. Serone, nevertheless believing he can seize the snake alive, attacks her. Cale stabs him with a tranquilizer dart before losing awareness once more himself, and Danny knocks Serone into the river.
Serone manages to seize as much as the group and captures Terri and Danny, using them as bait in an attempt to seize a 2nd, a lot large male black anaconda, measuring forty feet (12 m) individual. The snake assaults the pair, slowly suffocating them. Serone tries to catch the anaconda in a net, however it breaks loose and assaults him, ultimately swallowing him complete, even as Terri and Danny watch as they break out their bonds. The anaconda offers chase to Terri, who retreats into the constructing and reveals a nest full of new child anacondas.
